Using Supercomputing, Researchers Discover Hidden SARS-CoV-2 ‘Gate’ That Opens to Allow COVID Infection

Published August 19 in the journal Nature Chemistry, a research study led by Amaro, co-senior author Lillian Chong at the University of Pittsburgh, first author and UC San Diego graduate student Terra Sztain and co-first author and UC San Diego postdoctoral scholar Surl-Hee Ahn, describes the discovery of glycan “gates” that open to allow SARS-CoV-2 entry.

amaro covid
The glycan gate opens: Supercomputing-driven simulations depict the glycan N343 (magenta) acting as a molecular crowbar to pry open the SARS-CoV-2 spike’s receptor binding domain, or RBD (cyan), from a “down” to an “up” position. Credit: Terra Sztain, Surl-Hee Ahn, Lorenzo Casalino (Amaro Lab, UC San Diego).

Source: Mario Aguilera, UCSD

The post Using Supercomputing, Researchers Discover Hidden SARS-CoV-2 ‘Gate’ That Opens to Allow COVID Infection appeared first on HPCwire.

More Related Posts

How Artificial Intelligence, Machine Learning, and Simulation Work Together

As artificial intelligence (AI), machine learning (ML), and simulation revolutionize the way...

Quadruped learns how to adapt to tough terrain

Mount Etzel, in Switzerland, is ripe with challenges for a legged robot....

Robotic rover uses ‘rear rotor pedaling’ to avoid sand traps

As the National Aeronautics and Space Administration prepares to return to the...

Home

Highly Niched Headhunters Specialized in Physical AI/Robotics, High-Performance Computing, Unmanned/Autonomous Systems, Defense Technology and Energy.

Specializations

We recruit across complex engineering markets where understanding the technology is critical to finding the right talent.

How We Work

Overview of how PACE partners with teams: Our process, what clients get, and why PACE is different.

About Us

PACE’s story, values, and culture define how we operate and who we are.

News & Insights

Stay up to date on industry trends.

Contact

All the information needed for anyone interested in contacting us.